Leuprolide may cause shortterm within first 2 weeks of treatment increases in testosterone serum levels. Please see accompanying full prescribing information. For the role it plays in assisted reproductive technologies, leuprolide acetate is used to reduce the amount of estrogen and testosterone. Eligard, lupron, lupron depot leuprolide uses, side. Eligard is indicated for the palliative treatment of. Indications for lupron depot leuprolide acetate for depot. Indication for lupron depotped leuprolide acetate for. Leuprolide lupron, lupron depot, lupron depotped, eligard is a manmade hormone injection prescribed for the treatment of prostate cancer, endometriosis, fibroids, and central precocious. Leuprolide acetate is a synthetic nonapeptide that is a potent gonadotropinreleasing hormone receptor gnrhr agonist used for diverse clinical applications, including the treatment of. Menses usually returned within two months of cessation of therapy. Leuprolide depot injection or implant medication guide note.
Leuprolide reduces the amount of testosterone in men or. Transient worsening of symptoms, or the occurrence of additional signs and symptoms of prostate cancer, may. Lupron depot leuprolide acetate for depot suspension fda. Leuprolide fda prescribing information, side effects and. If you have questions about this medicine talk to your. Leuprolide definition of leuprolide by the free dictionary. Lupron injection leuprolide acetate rx only description. Leuprolide acetate definition of leuprolide acetate by. Reconstitution after calculating the number of vials needed, using aseptic technique, reconstitute each vial of thymoglobulin with 5 ml of sterile water for injection, usp swfi.
Eligard, lupron, lupron depot, lupron depotped, lupron depot3 month, lupron depot4 month, lupron3 month sr depot, prostap uk pharmacologic class. Leuprolide acetate is administered as a subcutaneous injection using insulin syringes. The kit consists of a twosyringe mixing system, a sterile safety needle table 3, a desiccant, and a package insert. Preparation and evaluation of a phospholipidbased injectable gel. Leuprolide injection lupron depotped is used to treat central. Leuprolide overstimulates the bodys own production of certain hormones, which causes that production to shut down temporarily. A drug that is a synthetic polypeptide analog of naturally. Leuprolide works by decreasing the amount of testosterone in males and estrogen in females made by the body.
Leuprorelin is the generic name of the drug and its inn and ban, while leuprorelin acetate is its banm and jan, leuprolide acetate is its usan and usp, leuprorelina is its dcit, and. When this is used for prostate cancer the resulting tumor flare can cause. Contraindications, warnings, and precautions in the norethindrone acetate package insert. Leuprolide acetate leuprolide acetate dose, indications. Leuprolide acetate injection is a sterile, aqueous solution intended for subcutaneous injection. Follow the pictorial directions on the reverse side of this package insert for. In other words, it tells the pituitary gland to ignore. The nci drug dictionary contains technical definitions and synonyms for drugsagents used to treat patients with cancer or conditions related to cancer.
Most types of prostate cancer need the male hormone testosterone to grow and spread. Denosumab versus zoledronic acid for treatment of bone. Leuprolide is used in men to treat the symptoms of prostate cancer but does not treat the cancer itself. Leuprolide is used to treat advanced prostate cancer in men. Insert the plunger rod into the prefilled syringe containing sterile water, usp, and screw the plunger rod clockwise to tighten. This label reflects clinical trials for lupron depot in prostate cancer in which the majority of the subjects studied were at least 65 years of age. See other lupron depot and lupron injection package inserts for other. Premenstrual syndrome, addback therapy, leuprolide acetate, gnrh a, tibolone. Lupron, the patient should be apprised of the potential hazard to the fetus. Initially, lupron, like other lhrh agonists, causes increases in serum levels of testosterone. Eligard is an injectable suspension of leuprolide acetate available in a single use kit.
Leuprolide lupron for prostate cancer chemoexperts. Leuprolide acetate lupron leuprolide acetate lupron is a gnrh agonist. The kit consists of a twosyringe mixing system, a sterile needle table 2, a silicone desiccant pouch to control moisture uptake, and a package insert for constitution and administration procedures. Leuprolide injection eligard, lupron depot is used to treat the symptoms associated with advanced prostate cancer. The kit consists of a twosyringe mixing system, a sterile needle or a sterile safety needle table 2, a silica gel desiccant pouch to control moisture uptake, and a package insert. It works by shrinking the abnormal uterine tissue that causes these. Leuprolide is used in women to treat symptoms of endometriosis. Norethindrone acetate as addback therapy with lupron 3. See the lupron depot ped package insert for the use of leuprolide acetate in children with central precocious puberty. Pdf dienogest is a selective progestin that has been investigated in a clinical trial programme for the treatment of. The injection site depends upon which formulation you are using, therefore the package insert should also be referenced to determine the appropriate injection site and method before. Leuprolide definition of leuprolide by medical dictionary. Learn more about the word leuprolide, its origin, alternative forms, and usage from wiktionary.
Definition of leuprolide acetate nci drug dictionary. Lupron, lupron depot leuprolide dosing, indications. These lupron depot formulations are not indicated for use in children. It is a synthetic form of the naturally occurring gonadotropinreleasing. Lupron depot leuprolide acetate for depot suspension. Pdf dienogest is as effective as leuprolide acetate in treating the.